Areas in which we have collaborated successfully with companies on include:
- Rapid batch to continuous assessment of fine chemical and pharmaceutical processes
- Accelerated process development of flavours and fragrance compounds
- Rapid technology transfer from laboratory to pilot scale of flavours and fragrance compounds
- Understanding and quantifying effects of physical phenomena on process efficiency for a phase II API
- Modelling and applying batch reactive distillation to complex esters used by the flavours and fragrance industry
- Modelling and applying batch reactive distillation to amidations and other equilibrium-limited reactions
- Increasing reaction efficiency (control of impurities, reduction of reagent excess, increased conversion, fewer process operations)
- Determination of reaction kinetics and thermodynamic properties using reaction calorimetry
- Modelling difficult problems of scale up and control for a diverse range of reaction types, including complex catalytic systems, systems involving simultaneous reactions, phases separations, and highly exothermic processes (including processes with secondary decomposition)
- Modelling multi-product plants for toll manufacturers to enable them to plan for future processes
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